Workshop on Advanced Radiotherapies and Diagnostic in Oncology

Differential biological response of cell cultures to single-pulse femtosecond and picosecond radiation at mean dose-rates between 10^10 and 10^13 Gy/s

12 mar 2026, 17:30

30m

Auditorium (Edificio A) (CNR - Area della Ricerca di Pisa)

KEYNOTES SESSION 3

Speaker

Hanna MAGUIRE (Queen's University Belfast)

Descrizione

We have recently developed novel irradiation platforms capable of delivering multi-Gy doses in a single pulse with durations ranging from 20 picosecond down to 150 femtoseconds (mean dose-rates up to 10^13 Gy/s). Irradiation of a series of normal and tumoral cell lines, in both 2D and 3D geometries, consistently indicate a significantly different response when compared to conventional and FLASH-like dose-rates, which promise significant benefits for radiotherapeutic applications. In this talk, we will review our current results in the area and discuss future steps towards in-vivo studies.